Cefotaxime Acid From Cefotaxime Sodium

  • Cefotaxime sodium | C16H16N5NaO7S2 - PubChem

    Cefotaxime Sodium is the sodium salt form of cefotaxime, a beta-lactam, third-generation cephalosporin antibiotic with bactericidal activity.Cefotaxime sodium

  • Cefotaxime | C16H17N5O7S2 - PubChem

    Cefotaxime is a cephalosporin compound having acetoxymethyl and [2- (2-amino-1,3-thiazol-4-yl)-2- (methoxyimino)acetyl]amino side groups. It has a role as a

  • Quality of cefotaxime sodium preparations

    Cefotaxime sodium (CAS 64485-93-4) is a semisynthetic cephalosporin derivative belonging to the third-generation cephalosporins. Owing to its broad antibacterial activity and its high resistance to beta-lactamases it can be used for a large variety of infections. In the present study the quality sta

  • Degradation kinetics in aqueous solution of cefotaxime ...

    The degradation kinetics of a 3- acetoxymethylcephalosporin , cefotaxime sodium salt, in aqueous solution investigated by HPLC under different conditions (pH, ionic strength, temperature) and using different buffers. The scheme of degradation involves a

  • Cefotaxime: Uses, Interactions, Mechanism of Action ...

    724 行 · Cefotaxime works by inhibiting bacterial cell wall biosynthesis. A positive feature of

  • CEFOTAXIME SODIUM - DrugFuture

    2011-4-22 · Cefotaxime sodium EUROPEAN PHARMACOPOEIA 7.0 Injection:10μL of the test solution and reference solutions (b), (c) and (d). Identification of impurities: use the chromatogram supplied with cefotaxime for peak identification CRS and the chromatogram obtained with reference solution (d) to identify thepeaksduetoimpuritiesA,B,C,EandF.

  • PRODUCT MONOGRAPH - Sanofi

    2020-12-14 · The sodium content of cefotaxime sodium (48.2 mg/g) should be taken into account in patients necessitating sodium restriction. Drug Interactions : Probenecid interferes with the renal tubular transfer of cephalosporins, thereby delaying their excretion and increasing their plasma concentrations.

  • Drug Shortage Detail: Cefotaxime Sodium Injection

    2021-10-8 · Cefotaxime Sodium powder for solution for injection, Hikma, 500 mg, vial, 10 count, NDC 00143-9930-10; Reason for the Shortage. Hospira has discontinued Claforan. Sanofi-Aventis manufactured Claforan for Hospira and is no longer making the product. Hikma is not currently marketing cefotaxime injection.

  • Page 1/8 Safety Data Sheet - Cayman Chemical Company

    2021-11-16 · Trade name: Cefotaxime (sodium salt) (Contd. from page 2) 53.1.21 4 First-aid measures · Description of first aid measures · After inhalation: Supply fresh air and to be sure call for a doctor. In case of unconsciousness place patient stably in side position for transportation.

  • 美国GlpBio - Cefotaxime (sodium salt) | cephalosporin ...

    Cefotaxime is a cephalosporin antibiotic. The cephalosporins, a class of β-lactam antibiotics originally derived from the fungus Acremonium, are indicated for the prophylaxis and treatment of infections caused by bacteria susceptible to this particular form of antibiotic. In vitro: Previous studies found that the in-vitro activity of ...

  • Process for the production of cefotaxime sodium - Justia

    2006-7-17 · Cefotaxime acid is converted to cefotaxime sodium (Formula VII); in a mixture of methanol and ethyl acetate in presence of triethylamine and sodium-2-ethylhexanonate. The product is precipitated by addition of excess ethyl acetate which on filtration provides final product (Formula VII) as solid mass.

  • Cefotaxime sodium | 64485-93-4 | 美国AbMole | Cefotaxim ...

    2021-12-15 · Cefotaxime sodium salt是第三代头孢菌素抗生素,是一种广谱的、具有抵抗大多数Gram-positive和Gram-negative细菌的抗菌剂。 立即从AbMole中国订购高品质Anti-infection抑制剂Cefotaxime sodium!

  • Cefotaxime: Uses, Interactions, Mechanism of Action ...

    Cefotaxime works by inhibiting bacterial cell wall biosynthesis. A positive feature of cefotaxime is that it display a resistance to penicillinases and is useful to treat infections that are resistant to penicillin derivatives. Mechanism of action.

  • Chemical Methodologies New Turbidimetric Method for ...

    2021-12-26 · Effect of sulfuric acid concentration Using cefotaxime sodium (8 mmol/L)-VOSO 4 (5 mmol/L) system, we prepared 140 μL sample volume at 1.8 ml/min flow rate for both lines, and a series of sulfuric acid solution (10- 100 mmol/L) as carrier stream (Figure 4 and Table1). It was found during working with acids (sulfuric

  • CEFOTAXIME SODIUM - DrugFuture

    2011-4-22 · Cefotaxime sodium EUROPEAN PHARMACOPOEIA 7.0 Injection:10μL of the test solution and reference solutions (b), (c) and (d). Identification of impurities: use the chromatogram supplied with cefotaxime for peak identification CRS and the chromatogram obtained with reference solution (d) to identify thepeaksduetoimpuritiesA,B,C,EandF.

  • PRODUCT MONOGRAPH - Sanofi

    2020-12-14 · The sodium content of cefotaxime sodium (48.2 mg/g) should be taken into account in patients necessitating sodium restriction. Drug Interactions : Probenecid interferes with the renal tubular transfer of cephalosporins, thereby delaying their excretion and increasing their plasma concentrations.

  • Spectrophotometric Determination Studies of

    2018-3-27 · experiments. Hydrochloric acid, sodium acetate, acetic acid, ammonia, methanol, ammonium chloride, cadmium chloride and copper chloride were purchased from Merck. Cefotaxime tablets were purchased from Ranbaxy laboratories Ltd. All the used chemicals were of analytical reagent grade; deionized water was used for diluting the reagents and samples.

  • Drug Shortage Detail: Cefotaxime Sodium Injection

    2021-10-8 · Cefotaxime Sodium powder for solution for injection, Hikma, 500 mg, vial, 10 count, NDC 00143-9930-10; Reason for the Shortage. Hospira has discontinued Claforan. Sanofi-Aventis manufactured Claforan for Hospira and is no longer making the product. Hikma is not currently marketing cefotaxime injection.

  • Effect of novel drug (derived from curcumin and

    2020-12-4 · Cefotaxime produced significant increase in kidney function tested such as urea, creatinine, calcium, sodium and potassium as compared to control group. Also, cefotaxime caused an increase in liver function tests such as alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase and total bilirubin.

  • Cefotaxime sodium | 64485-93-4 | 美国AbMole | Cefotaxim ...

    2021-12-15 · Cefotaxime sodium salt是第三代头孢菌素抗生素,是一种广谱的、具有抵抗大多数Gram-positive和Gram-negative细菌的抗菌剂。 立即从AbMole中国订购高品质Anti-infection抑制剂Cefotaxime sodium!

  • Cefotaxime Sodium - pipitech

    Cefotaxime Impurity M(E-Cefotaxime Impurity B,E-Deacylation ATMAA, E-Deacylation Aminothiamic Acid) Catalog No: PI00010009 Product Name: Cefotaxime Impurity M(E-Cefotaxime Impurity B,E-Deacylation ATMAA, E-Deacylation Aminothiamic Acid)

  • Synthesis of cefotaxime sodium salt | Download Scientific ...

    Cefotaxime sodium salt was synthesized by acylating 7-amino cephalosporanic acid with 2-[2'-chloracetamidothiazole-4-yl]-2-(syn)-methoxy-imino acetic chloride in

  • Cefotaxime - FDA prescribing information, side effects and ...

    2021-12-22 · Cefotaxime for Injection, USP contains approximately 50.5 mg (2.2 mEq) of sodium per gram of Cefotaxime activity. Solutions of Cefotaxime for injection range from very pale yellow to light amber depending on the concentration and the diluent used. The pH of the injectable solutions usually ranges from 4.5 to 6.5.

  • Cefotaxime sodium, powder for injection, equivalent to ...

    2021-8-13 · CEFOTAXIME Cefotaxime sodium, powder for injection, equivalent to Cefotaxime 500 mg, 1 g and 2 g PRESENTATION Cefotaxime is a white to slightly yellowish powder, which, when dissolved in Water for Injections B.P., forms a straw coloured solution given by intravenous or intramuscular administration.

  • Chemical Methodologies New Turbidimetric Method for ...

    2021-12-26 · Effect of sulfuric acid concentration Using cefotaxime sodium (8 mmol/L)-VOSO 4 (5 mmol/L) system, we prepared 140 μL sample volume at 1.8 ml/min flow rate for both lines, and a series of sulfuric acid solution (10- 100 mmol/L) as carrier stream (Figure 4 and Table1). It was found during working with acids (sulfuric

  • Cefotaxime Impurity Q,E- Cefotaxime Acid,头孢噻肟杂质Q ...

    头孢噻肟杂质Q,反式氨噻肟酸 Catalog No: PI00010015 Product Name: Cefotaxime Impurity Q,E- Cefotaxime Acid

  • Cefotaxime 1g powder for solution for injection vials ...

    2017-12-11 · Cefotaxime sodium may be administered intravenously, by bolus injection or infusion, or intramuscularly. The dosage, route and frequency of administration should be determined by the severity of infection, the sensitivity of causative organisms and condition of the patient. Therapy may be initiated before the results of sensitivity tests are known.

  • PRODUCT MONOGRAPH - Sanofi

    2020-12-14 · The sodium content of cefotaxime sodium (48.2 mg/g) should be taken into account in patients necessitating sodium restriction. Drug Interactions : Probenecid interferes with the renal tubular transfer of cephalosporins, thereby delaying their excretion and increasing their plasma concentrations.

  • Drug Shortage Detail: Cefotaxime Sodium Injection

    2021-10-8 · Cefotaxime Sodium powder for solution for injection, Hikma, 500 mg, vial, 10 count, NDC 00143-9930-10; Reason for the Shortage. Hospira has discontinued Claforan. Sanofi-Aventis manufactured Claforan for Hospira and is no longer making the product. Hikma is not currently marketing cefotaxime injection.